ABSTRACT
Objective: A foreign body aspiration in the tracheobronchial tree is a dangerous medical condition in the childhood period. Although rigid bronchoscopy is a safe procedure, it may cause complications. The aim of this study was to present our bronchoscopy experience and to evaluate the efficacy of pre-operative administration of nebulized albuterol and budesonide combination for reducing intra-operative complications in foreign body aspirated cases
Methods: In this retrospective study our pediatric cases in which a foreign body was removed from tracheobronchial tree in last 8 years were analyzed. After excluding the patients who needed emergent and negative bronchoscopies, the remaining clinically stable 84 patients were compared for the effects of preoperative administration of nebulized albuterol and budesonide combination on bronchoscopy complications
Results: There were 51 boys [60.3%] and 33 girls [39.7%]. There were 38 children in the non-nebulized group and 46 children in the nebulized group. We found that the combined albuterol and budesonide nebulization decrease complications such as arterial oxygen desaturation [p<0.05], and bronchospasm [p<0.05] during the bronchoscopic intervention
Conclusion: Preoperative nebulization of albuterol and budesonide combination may decrease perioperative complications of bronchoscopy
ABSTRACT
The purpose of this study was to determine the impact of mean platelet volume [MPV] on the frequency and severity of vaso-occlusive and cerebrovascular events in patients with sickle cell anemia [SCA]. The 238 cases diagnosed with SCA were evaluated retrospectively with respect to the occurrence of painful crisis for the previous year. The incidence, severity and type of the vaso-occlusive crises of the patients with SCA between March 2010 and March 2011 were recorded. The last MPV values in patients who were free of erythrocyte transfusion for the last three months and who had no current vaso-occlusive crises were evaluated. All the patients were grouped according to the frequency of the crises for the previous year preceding the data collection. Group 1: 1 to 3 crises, Group 2: 4 to 5 and Group 3: 6 or more crises annually. In accordance with the results obtained during the evaluation of the cases diagnosed with sickle-cell anemia, MPV value was found to be significantly higher in patients with cerebrovascular events. Also MPV values increased with increasing incidence of the crises [r=0.297] [p=0.001]. One of the contributing factors for this clinical heterogeneity may be related to the MPV values in patients with sickle cell anemia. The higher MPV values may be an early predictor of future cerebrovascular events in patients with sickle cell anemia and may require close follow-up and additional measures
ABSTRACT
To investigate resistant microorganisms in nasal mucosa of children with Familial Mediterranean Fever. The study was conducted from March to May 2013 at Mustafa Kemal University, Turkey, and comprised children with Familial Mediterranean Fever and healthy controls. All subjects had no history of antibiotic or local and/or systemic steroid use within the preceding 2 weeks. Nasal swab samples were obtained from all the subjects. Strain identification was done by using standard methods. SPSS 13 was used for statistical analysis. Of the 151 subjects in the study, 73[48.34%] were cases and 78[51.65%] were controls. Among the cases, there were 26[35.6%] girls, while among the controls, there were 40[51.3%] girls [p=0.052]. The mean age of the cases was 7.78 +/- 3.34 years [range: 3-15 years], while it was 8.15 +/- 2.71 years [range: 3-16] among the controls [p=0.208]. Methicillin-resistant coagulase-negative staphylococcus and methicillin-resistant staphylococcus aureus were isolated in both the groups. The growth rate of resistant bacteria was 63% [n=46] in the cases, in the controls [p=0.003; odds ratio [OR]: 2.7; 95% confidence interval [CI]: 1.4-5.2]. Among the controls, history of hospitalisation increased the risk for the presence of resistant bacteria by 7.7 fold [OR: 7.7; 95% CI: 1.4 - 40.4]. Higher rates of resistant bacteria showed that they were at risk of comorbidities related to antibiotic resistance